KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
22.42
Human Site:
Y1044
Identified Species:
35.24
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
Y1044
F
Y
N
F
D
K
N
Y
K
D
W
Q
S
A
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
Y1044
F
Y
N
F
D
K
N
Y
K
D
W
Q
S
A
V
Dog
Lupus familis
XP_531814
1283
145094
L1002
P
M
C
R
P
V
I
L
L
P
E
E
G
T
P
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
H1041
F
C
N
F
D
K
N
H
K
D
W
Q
S
A
V
Rat
Rattus norvegicus
XP_002726765
1361
151628
H1044
F
Y
N
F
D
K
N
H
K
D
W
Q
S
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
S1150
F
Y
N
F
D
K
N
S
Q
D
W
Q
T
A
V
Frog
Xenopus laevis
NP_001089247
1340
149481
Y1024
F
Y
N
F
D
K
N
Y
K
E
W
Q
T
A
V
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
Y1045
F
Y
N
F
D
K
N
Y
K
D
W
Q
T
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
S916
I
C
V
P
E
L
V
S
D
A
D
Q
P
F
I
Honey Bee
Apis mellifera
XP_392346
1120
127429
E846
D
V
L
I
S
L
T
E
Y
A
F
S
G
D
M
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
F912
M
C
M
P
E
F
D
F
N
A
T
D
P
Y
L
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
Y1016
F
H
K
F
D
E
H
Y
K
S
W
D
A
A
I
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
P1008
S
A
K
K
L
G
H
P
V
L
R
S
D
S
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
Q997
I
G
R
F
C
E
H
Q
E
K
W
R
Q
L
V
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
I968
K
D
F
I
P
N
D
I
E
L
G
K
E
Q
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
0
N.A.
86.6
93.3
N.A.
N.A.
80
86.6
93.3
N.A.
6.6
0
0
46.6
P-Site Similarity:
100
N.A.
100
6.6
N.A.
93.3
100
N.A.
N.A.
93.3
100
100
N.A.
20
13.3
26.6
80
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
0
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
20
0
0
7
54
0
% A
% Cys:
0
20
7
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
54
0
14
0
7
40
7
14
7
7
0
% D
% Glu:
0
0
0
0
14
14
0
7
14
7
7
7
7
0
0
% E
% Phe:
54
0
7
60
0
7
0
7
0
0
7
0
0
7
0
% F
% Gly:
0
7
0
0
0
7
0
0
0
0
7
0
14
0
0
% G
% His:
0
7
0
0
0
0
20
14
0
0
0
0
0
0
0
% H
% Ile:
14
0
0
14
0
0
7
7
0
0
0
0
0
0
14
% I
% Lys:
7
0
14
7
0
47
0
0
47
7
0
7
0
0
0
% K
% Leu:
0
0
7
0
7
14
0
7
7
14
0
0
0
7
14
% L
% Met:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
47
0
0
7
47
0
7
0
0
0
0
0
0
% N
% Pro:
7
0
0
14
14
0
0
7
0
7
0
0
14
0
14
% P
% Gln:
0
0
0
0
0
0
0
7
7
0
0
54
7
7
0
% Q
% Arg:
0
0
7
7
0
0
0
0
0
0
7
7
0
0
0
% R
% Ser:
7
0
0
0
7
0
0
14
0
7
0
14
27
7
0
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
7
0
20
7
0
% T
% Val:
0
7
7
0
0
7
7
0
7
0
0
0
0
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% W
% Tyr:
0
40
0
0
0
0
0
34
7
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _